This week, I wanted to talk about the latest video game sensation: Big Vampire Lady from Resident Evil VIllage. Lady Dimitrescu has been drawing a lot of attention for her incredible height and incredible bust, but as high resolution images of her started to spread this week, people also noticed her skin seemed a little odd. But it turns out… she’s not the only one with unusual skin. I talk about my own skin as I discuss the genetics of a condition I have called ichthyosis and how it may relate to the design of Lady Dimitrescu’s skin and also revisit how I feel about that kind of representation in games.